How Many Calories Is in a Slice of Pepperoni Pizza?

Introduction

Pepperoni pizza is an all-American favorite—perfect for parties, game nights, and quick dinners. But how many calories are in a slice, and what else are you eating with every bite? Whether you’re tracking calories, keeping an eye on your macros, or just interested in healthier eating, understanding the nutrition facts of a pepperoni pizza slice will help you enjoy your meal mindfully.

Calorie Estimates for a Slice of Pepperoni Pizza

The calorie count of a pepperoni pizza slice varies based on crust, cheese quantity, pepperoni load, and even which pizzeria you order from. However, averages for a regular-crust, 14-inch pizza (the standard U.S. size, cut into 8 slices) are as follows:

• Calories: 250–350 per slice
• Fat: 10–15g per slice
• Protein: 10–15g per slice
• Carbs: 25–35g per slice
• Sodium: 500–700mg per slice
  

A “small” slice (from a 10–12-inch pizza) is usually at the lower end of these ranges.

Nutrition Facts for a Slice of Pepperoni Pizza

Macro & Micronutrient Breakdown

Values vary by size, brand, and exact toppings.

Calories in 1 Slice of Pepperoni Pizza (Detailed Chart)

Always check your local or online menu for precise numbers—crusts, cheese and portion sizes can shift nutritional content!

Nutrition Facts Per Slice

A pepperoni pizza slice provides:

• Protein: Essential for building & repair, largely from cheese/meat.
• Carbs: The crust is the main contributor—prefer thin for fewer carbs.
• Fat: Pepperoni and cheese are the primary sources (including saturated fat).
• Sodium: Pepperoni is salty, so watch your blood pressure if you eat multiple slices.
• Micronutrients: Calcium from cheese, iron from flour and pepperoni, small amounts of vitamin A and minerals.
  

Factors Affecting Nutrition

• Crust type: Thin crust = fewer calories/carbs; deep dish/pan/stuffed
• Topping amount: Extra cheese or double pepperoni can increase calories by 20–40%.
• Slice size: Smaller pizzas and more slices per pie mean smaller (lower-calorie) pieces.
• Regional/brand differences: National chains (Domino’s, Pizza Hut, Papa John’s) each have online tools to check calories by slice size or customization

Health Considerations Beyond Calories

• Saturated Fat: Pepperoni is high in saturated fat, which can impact heart health when consumed in excess.
• Sodium: One or two slices often bring you near 20–30% of the daily recommended sodium intake.
• Refined Carbs: Most pizzerias use white flour crust, leading to a high glycemic index.

However, you can offset these with side salads, veggies, and balanced portions—making pepperoni pizza an occasional treat in a healthy diet.

So, How Can You Be More Precise?

• Use online calculators: Domino’s, Pizza Hut, and Papa John’s provide accurate nutritional info based on size, crust, and toppings selections.
• Weigh your slice: If homemade or from a local shop, weighing your slice and comparing it to standard nutrition values per 100g helps get exact numbers.
• Calorie tracking apps: U.S.-based calorie trackers like MyFitnessPal and FatSecret have listings for dozens of brands.

Enjoying Your Pizza Mindfully

• Stick to 1–2 slices per meal
• Pair with a fiber-rich side like a salad
• Choose thin crust (or cauliflower crust) to reduce calories/carbs
• Ask for “light cheese” or “half pepperoni” to cut fat
• Eat slowly and savor each bite for greater satisfaction

Frequently Asked Questions (FAQs)

• How many calories are in 2 large slices of pepperoni pizza?
  If each slice is 290–350cal, then two have about 580–700cal—add more if slices are “large” or loaded with cheese.
• How many carbs are in pepperoni pizza?
  A standard slice (regular crust) has about 30–42g of carbs. Thin crust drops closer to 25g, and deep dish rises to 40g+ per slice.
• What is the nutritional value of pepperoni pizza?
  Calories: 250–350 per slice
  Fat: 10–15g
  Protein: 10–15g
  Carbs: 25–35g
  Fiber: 1–2g
  Sodium: 500–700mg
  Also: Calcium, iron, small amounts of vitamins A, K, B12, and zinc.